Successful therapeutic response of resistant cases of mucocutaneous leishmaniasis to a very low dose of antimony

Two mucocutaneous leishmaniasis cases resistant to therapy are reported here. After the failure of initial therapies (antimony, amphotericin B and/or pentamidine) patients received a low-dose schedule: one ampoule of meglumine antimoniate (405mg of pentavalent antimony [Sb v]) by intramuscular injection, three times a week until complete healing of the lesions. One patient was cured with a total of 30 ampoules in 10 weeks and the other received 36 ampoules in 12 weeks. Both remain clinically cured after one year of follow-up.

Saved in:
Bibliographic Details
Main Authors: Oliveira-Neto,Manoel Paes de, Mattos,Marise da Silva
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Medicina Tropical - SBMT 2006
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822006000400011
Tags: Add Tag
No Tags, Be the first to tag this record!