Acute disseminated histoplasmosis and endocarditis

Acute disseminated histoplasmosis is a frequent condition in HIV carriers. Thirty-five cases of endocarditis caused by Histoplasma capsulatum have been reported in international literature, and all these descriptions correspond to a context of subacute disseminated histoplasmosis. This paper presents the case of a HIV-positive patient with fever, dyspnea, weight loss, vomiting and polyadenopathies to whom histoplasmosis was diagnosed following blood-cultures and isolation of the agent responsible for cutaneous lesions, and in whom aortic-valve vegetations were found during an echocardiogram. The patient was treated with amphotericin B and had a good outcome; subsequent echocardiograms showed no vegetations. Literature on the subject is reviewed, with special emphasis on diagnosis and treatment of previously described cases.

Saved in:
Bibliographic Details
Main Authors: SCAPELLATO,Pablo G., DESSE,Javier, NEGRONI,Ricardo
Format: Digital revista
Language:English
Published: Instituto de Medicina Tropical de São Paulo 1998
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651998000100005
Tags: Add Tag
No Tags, Be the first to tag this record!