Amastigotes forms of Trypanosoma cruzi detected in a renal allograft
Trypanosoma cruzi, the causative agent of Chagasdisease assumes two distinct forms in vertebrate hosts: circulating trypomastigote and tissular amastigote. This latter form infects predominantly the myocardium, smooth and skeletal muscle, and central nervous system. The present work describes for the first time the detection of amastigote forms of T. cruzi in the renal parenchyma of a kidney graft recipient one month after transplantation. The patient was serologically negative for Chagasdisease and received no blood transfusion prior to transplant. The cadaver donor was from an endemic area for Chagasdisease. The recipient developed the acute form of the disease with detection of amastigote forms of T. cruzi in the renal allograft biopsy and circulating trypomastigote forms. The present report demonstrates that T. cruzi can infect the renal parenchyma. This mode of transmission warrants in endemic areas of Chagasdisease
| Main Authors: | , , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
Instituto de Medicina Tropical de São Paulo
1997
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| Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651997000400008 |
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