Antibody to human T-lymphotropic virus in a patient with Guillain-Barré syndrome (case report)

Serum sample obtained from a male, 12 year old patient suffering from Guillain-Barré syndrome (GBS) was positive for human T-lymphotropic virus (HTLV-I) antibody by the enzyme-linked immunosorbent assay (ELISA) and the Western Blot analysis (WB). Attempts to isolate enteroviruses (including poliovirus) from faecal material in both tissue culture and suckling mice were unsuccessful; in addition, acute and convalescent paired serum samples did not show any evidence of recent poliovirus infection when tested against the three serotypes. Specific tests for detection of Epstein-Barr virus infection were not performed; however, the Paul-Bunnel test yielded negative results. ELISA for detection of anti-cytomegalovirus IgM was also negative. The concomitant occurrence of either adult T cell leukemia (ATL) or lymphoma was not recorded in this case.

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Bibliographic Details
Main Authors: Nakauchi,C.M., Linhares,A.C., Gomes,M.L.C., Maruyama,K., Kanzaki,L.I., Azevedo,V.N.
Format: Digital revista
Language:English
Published: Instituto de Medicina Tropical de São Paulo 1991
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651991000400015
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