Differences in the antigenic profile of bloodstream and cell culture derived trypomastigotes of Trypanosoma cruzi

A comparative study of the antigenic profile of bloodstream and cell culture derived trypomastigotes showed many differences in their components. Using mouse anti-T. cruzi antibodies the differences were located mostly in the 120 kDa band, whereas using chagasic patient sera the differences were located in the 85 and 52 kDa bands. These findings might explain known physiological differences between trypomatigotes obtained from cell culture and from infected blood. A brief report of this work has already been published9.

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Bibliographic Details
Main Authors: Silva,Ana M. M. Da, Brodskyn,Cláudia I., Takehara,Harumi A., Mota,I.
Format: Digital revista
Language:English
Published: Instituto de Medicina Tropical de São Paulo 1989
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651989000300003
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