American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice
Germfree (GF) and conventional (CV) CFW (LOB) mice and Wistar and Sprague-Dawley rats were infected with Trypanosoma cruzi. The disease was more severe in the GF than in the CV animals as revealed by: (1) an earlier and more intense parasitemia; (2) a more precocious mortality; (3) a twice enlarged spleen: (4) a more intense cell and tissue parasitism; (5) visceral signs of cardiac failure.
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Main Authors: | , , , , |
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Format: | Digital revista |
Language: | English |
Published: |
Instituto de Medicina Tropical de São Paulo
1987
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Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651987000500004 |
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