American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice

Germfree (GF) and conventional (CV) CFW (LOB) mice and Wistar and Sprague-Dawley rats were infected with Trypanosoma cruzi. The disease was more severe in the GF than in the CV animals as revealed by: (1) an earlier and more intense parasitemia; (2) a more precocious mortality; (3) a twice enlarged spleen: (4) a more intense cell and tissue parasitism; (5) visceral signs of cardiac failure.

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Bibliographic Details
Main Authors: Silva,Marcelo E., Evangelista,Elizio A., Nicoli,Jacques R., Bambirra,Eduardo A., Vieira,Enio C.
Format: Digital revista
Language:English
Published: Instituto de Medicina Tropical de São Paulo 1987
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651987000500004
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