Actividad bactericida de superficies de cobre frente a bacterias asociadas a infecciones nosocomiales, en un modelo in vitro de adherencia y sobrevivencia
Background: Copper has a bactericidal activity against a series of bacterial strains. Aim: To measure resistance to bacterial adherence of copper (Cu) and stainless steel (SS) metal coupons. Material and Methods: Bacterial strains causing nosocomial infections in Chile were analyzed. Bacterial adherence was studied using apreviously described method based on a system of metal coupons that are immersed in culture media containing the bacteria ofinterest at room temperature. Results: Adherence to Cu and SS coupons was differentfor Methicillin-resistant Staphylococcus aureus (MRSA), Klebsiella pneumoniae and Acinetobacter baumannii strains. For these strains, no adherence to Cu coupons occurred during the 48 h observation period compared to a rapidly increasing adherence to SS coupons, with a final colony count of 1.00E + 07 cfu/mL. For two different Pseudomonas aeruginosa clinical strains, inhibition of adherence was not observed on Cu coupons, and colony counts were similar for Cu and SS using the standard inoculum (2-3 xlO7 cfu).Apartial decrease in adherence was observed for Cu but not for SS coupons, when a lower inoculum was used. Conclusions: Copper surfaces represent an interesting option to reduce bacterial contamination in the hospital environment due to its resistance to bacterial adhesión ofmost ofthe common nosocomial bacterial strains.
| Main Authors: | , , , |
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| Format: | Digital revista |
| Language: | Spanish / Castilian |
| Published: |
Sociedad Médica de Santiago
2013
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| Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872013000300002 |
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