Neumonía eosinofílica inducida por mesalazina: Caso clínico

A 50 years old male with a diagnosis of ulcerative colitis treated with mesalazine, developed after 2 months of treatment, cough, fever and progressive dyspnea. Chest X ray examination and CT scan showed pulmonary infiltrates in the right upper lobe that subsequently involved both lower lobes. A biopsy, made through videothoracoscopy, showed an eosinophilic pneumonia. After the discontinuation of mesalazine and the use of glucocorticoids, the respiratory involvement resolved, and pulmonary infiltrates regressed. Mesalazine is widely used in the treatment of inflammatory bowel diseases. Pulmonary toxicity is an uncommon complication of mesalazine treatment. Nevertheless, this complication should be considered in patients that use it and develop respiratory symptoms (Rev Méd Chile 2003; 131: 81-84)

Saved in:
Bibliographic Details
Main Authors: Pérez C,Carlos, Errázuriz C,Isabel, Brockmann V,Pablo, González B,Sergio, Cofré L,Cecilia
Format: Digital revista
Language:Spanish / Castilian
Published: Sociedad Médica de Santiago 2003
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000100013
Tags: Add Tag
No Tags, Be the first to tag this record!