Apoplejía en metástasis hipofisiaria de carcinoma de células renales: Caso clínico con siete años de seguimiento

We report a man in whom a 15 cm. renal tumor was excised at the age of 49. The pathological examination showed a clear cell carcinoma. Five years later, he presented with headache, vomiting and unilateral palpebral ptosis. Imaging studies showed a sellar tumor with pituitary apoplexy. The tumor was excised and the pathological study disclosed a clear cell tumor, positive for vimentin, cytokeratins AE1 and AE3 and immunohistochemically negative for LH, TSH, ACTH and GH. Considering the similar histopathological features, it was considered as a metastasis of the renal tumor. The patient was supplemented with thyroid, adrenal and gonadal hormones. Seven years later, he presented a new tumor in the remaining kidney, that corresponded to a cystic papillary renal cell carcinoma. Afterwards, he presented a transitional urinary bladder tumor. Mortality associated to renal cell tumors is 90% at 5 years, and pituitary metastases are extraordinarily uncommon (Rev Méd Chile 2000; 128: 1015-8).

Bibliographic Details

Main Authors:	Quevedo L,Iván, Rodríguez Portale,José A, Rosenberg G,Helmar, Mery S,Jorge
Format:	Digital revista
Language:	Spanish / Castilian
Published:	Sociedad Médica de Santiago 2000
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000000900009
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