Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico

Background: Sixty percent of adults has typical symptoms of gastroesophageal reflux in Chile. Aim: To report the clinical and laboratory features of patients with gastroesophageal reflux. Patients and methods: Five hundred thirty four patients (255 male) with gastroesophageal reflux were included in a prospective protocol that included clinical analysis, manometry and endoscopy in all patients, barium swallow in 427, scintigraphy in 195, acid reflux test in 359, 24 h pH in 175, and differential potential of gastroesophageal mucosa in 73 patients. Results: There was no correlation between the severity of symptoms and the endoscopical severity. Patients with Barret esophagus were 12 years older, were male in a greater proportion and had a higher proportion of manometrically incompetent sphincters than patients with esophageal reflux but without esophagitis or with erosive esophagitis. Severity of acid reflux, measured with 24 h pH monitoring was proportional to the endoscopical damage of the mucosa. There was a close relationship between the mucosal change limit determined with differential potentials and with endoscopy. No short esophagi were found. Conclusions: Patients with symptoms of gastroesophageal reflux must be assessed using several objective measures to determine the severity of their pathological alterations.

Bibliographic Details

Main Authors:	Csendes J,Attila, Burdiles P,Patricio, Maluenda G,Fernando, Cortés D,Claudio, Korn B,Owen, Rojas C,Jorge, Tepper J,Patricio, Huertas M,César, Sagastume G,Héctor, Puente Q,Guillermo, Quezada M,Fernando, Csendes G,Paula
Format:	Digital revista
Language:	Spanish / Castilian
Published:	Sociedad Médica de Santiago 1998
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98871998000700004
Tags:	Add Tag No Tags, Be the first to tag this record!