Chemical composition and larvicidal activity of essential oil of the bark of Citrus sinensis (L.) Osbeck

SUMMARY Aim: We determined the chemical composition and larvicidal activity of the essential oil distilled from the Citrus sinensis (L.) Osbeck husks and the pattern of the major constituent. Materials and methods: For this, we distill the oil by hydrodistillation, identify the components by gas chromatography coupled with mass spectrometry (GC-MS), test the larvicidal activity against Aedes aegypti and calculate the lethal concentration at 50% (LC50) by the Reed-Muench method and the confidence interval by the Pizzi method for both oil and standard. Results: It showed that the oil consists mostly of limonene and showed larvicidal activity (LC50 of 199.01 (± 2.10) μg-mL-1) greater than the lemonade standard (126.03 (± 2.09) μg-mL-1). Conclusion: Therefore, we conclude that distilled oil has the potential to replace chemical larvicides.

Bibliographic Details

Main Authors:	Barros Gomes,Paulo Roberto, de Assunção,Gilson Vitorino, Oliveira Everton,Gustavo, Souza de Lima,Helson, Fernandes de Araújo,Jorge Ricardo, Fonseca Silva,Eduardo, Vasconcelos Melo,Andréa, Costa Louzeiro,Hilton, Batista Reis,Jonas, Mouchrek Filho,Victor Elias
Format:	Digital revista
Language:	English
Published:	Departamento de Farmácia, Facultad de Ciencias, Universidade Nacional da Colombia 2021
Online Access:	http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0034-74182021000100048
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