Use of bedaquiline during pregnancy in a patient with MDR-TB. First case reported in Mexico
Abstract: Treatment of rifampin-resistant and multidrug-resistant tuberculosis in pregnant women is more complicated since little is known about the safety of second-line antituberculosis drugs during pregnancy and lactation. Drug-resistant tuberculosis, not having many options in the past, has been treated with regimens that include drugs with teratogenic potentials, such as thioamides and second-line injectables. Currently, there are new oral drugs, including bedaquiline, for the treatment of drug-resistant disease; however, the safety of bedaquiline during pregnancy and lactation has not been satisfactorily demonstrated so far. We report the first case in Mexico treated with a regimen that includes bedaquiline for multidrug-resistant tuberculosis during pregnancy, with favorable results, and without maternal-fetal complications.
| Main Authors: | , , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
Sociedad Mexicana de Neumología y Cirugía de Tórax; Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas; Sociedad Cubana de Neumología; Sociedad Paraguaya de Neumología; Sociedad Boliviana de Neumología.
2022
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| Online Access: | http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0028-37462022000200138 |
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