CT hypodensity on cerebral white matter in Wilson's disease

Wilson's disease in an autosomal recessive disorder of copper metabolism where systemic manifestations are secondary to thei accumulation of copper in hepatic, nervous and other tissues. In CNS, the structural lesions most commonly found by CT scan are ventricular dilatation, cortical atrophy, basal ganglia hyperdensities, and brainstem and cerebellar atrophy. Degenerative changes of cerebral white matter seen on early anatomo-pathologic studies, but were almost never found on CT scan from recently described patients. We report a case of Wilson's disease with an unusually rapid deterioration where asymmetric low-densities in the subcortical white matter were disclosed by CT scan.

Saved in:
Bibliographic Details
Main Authors: Jardim,Laura B., Carneiro,Aníbal, Hansel,Suzana, Rieder,Carlos R. M., Giugliani,Roberto
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 1991
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1991000200017
Tags: Add Tag
No Tags, Be the first to tag this record!