Ischemic cerebral changes in the chronic chagasic cardiopathy

The pathological systematized study of the brain of 31 cases of the chronic cardiac form of Chagas' disease was undertaken. Elective parenchymatous necrosis was found in 64.5% of cases, mainly in cerebellar Purkinje cells, and in thalamic nuclei. Also found were multiple foci of old micronecrosis (51.6%) mostly in the cerebral cortex, old cerebral infarcts (22.6%), cortical laminar necrosis (16.1%) and cerebral cortical atrophy (3.2%). These findings are not specific and can be explained by thromboembolic phenomena and hypoxemia following from congestive heart failure and disturbances of the cardiac rhythm.

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Bibliographic Details
Main Author: Pitella,José Eymard Homem
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 1984
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1984000200002
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