Celiac disease screening in patients with scleroderma

Both celiac disease and scleroderma have autoimmune etiology and affect the bowel causing diarrhea. As an association of autoimmune disease in a single individual is not rare, it is important to know if a patient with scleroderma may also have celiac disease. To analyze this we studied 105 scleroderma patients and 97 volunteers for IgA-EmA by indirect immunofluorescence assay. We could not find a higher prevalence of this autoantibody in scleroderma patients. The authors conclude that there is no need to screen scleroderma patients with diarrhea for celiac disease unless there is a clear clinical indication for this.

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Bibliographic Details
Main Authors: Nisihara,Renato, Utiyama,Shirley Rosa, Azevedo,Pedro Ming, Skare,Thelma Larocca
Format: Digital revista
Language:English
Published: Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia e Outras Especialidades - IBEPEGE. 2011
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032011000200014
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