Histopathological changes of lymphatic malformation after bleomycin injection

ABSTRACT Lymphatic malformation is a rare orbital tumor that used to be treated surgically, with high complication rates, or recently with intralesional bleomycin injection. We report for the first time the histopathological changes of eyelid lymphatic malformation after water-soluble intralesional bleomycin injection in a 20-year-old woman who had unsuccessful orbital surgical debulking during childhood. The changes confirmed the assumption of fibrosis induced by intralesional bleomycin injection. The minimal bleeding during surgical intervention made it much easier than the usual lymphatic malformation bloody procedure, without postoperative recurrences and with favorable aesthetic outcomes.

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Bibliographic Details
Main Authors: Al-Faky,Yasser H, Alkatan,Hind Manaa
Format: Digital revista
Language:English
Published: Conselho Brasileiro de Oftalmologia 2022
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492022005005214
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