Complete ¹H and 13C NMR assignments and anti fungal activity of two 8-hydroxy flavonoids in mixture

A mixture of the two new flavonols 8-hydroxy-3, 4', 5, 6, 7-pentamethoxyflavone (1) and 8-hydroxy-3, 3', 4', 5, 6, 7-hexamethoxyflavone (2) was isolated from a commercial sample of Citrus aurantifolia. An array of one- (¹HNMR, {¹H}-13C NMR, and APT-13C NMR) and two-dimensional NMR techniques (COSY, NOESY, HMQC and HMBC) was used to achieve the structural elucidation and the complete ¹H and 13C chemical shift assignments of these natural compounds. In addition, the antifungal activity of these compounds against phytopathogenic and human pathogenic fungi was investigated.

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Bibliographic Details
Main Authors: Johann,Susana, Smânia-Jr,Artur, Pizzolatti,Moacir G., Schripsema,Jan, Braz-Filho,Raimundo, Branco,Alexsandro
Format: Digital revista
Language:English
Published: Academia Brasileira de Ciências 2007
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652007000200004
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