Efectos del clenbuterol oral sobre la glicemia y kalemia en equinos fina sangre inglés Clínicamente sanos

In order to investigate the effect of beta agonist adrenergic drugs on body potassium distribution, blood samples were obtained from 30 healthy thoroughbred horses trained to horsemanship competitions, in fasting and resting conditions, before and after clenbuterol administration at eight o'clock in the morning. In each sample were determined blood glucose and plasmatic potassium concentrations.One hour after oral administration of' clenbuterol (0.8 µg/Kg), plasmatic potassium concentration was significatively lower than control values (3.9 ± 0.5 and 4.2 ± 0.2 mmol/l, respectively; p < 0.05), while blood glucose concentration (91.4 ± 20.0 mg/dl) was not significatively different from control (87.4 ± 18.9 mg/dl). At the end of' two hours after clenbuterol administration, plasma tic potassium concentration was maintained signi­ficatively lower than control values (3.8 ± 0.6 mmol/l; p < 0.05), ivhile blood glucose concentration was 90.3 ± 17.2 mg/dl. This results are indicating the participation of beta agonists, like clenbuterol, in the regulation of plasmatic potassium concentration.

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Bibliographic Details
Main Authors: Martínez P., Ramón, Godoy P., Adolfo, Pizarro S., Eduardo, White O., Allan
Format: Digital revista
Language:spa
Published: Universidad de Chile. Facultad de Ciencias Veterinarias y Pecuarias 1990
Online Access:https://avancesveterinaria.uchile.cl/index.php/ACV/article/view/10397
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