Plasma tocopherol in sheep and cattle after ingesting free or acetylated tocopherol

Two trials were carried out to evaluate the bioavailability of dl-α-tocopherol and dl-α-tocopherol acetate administered to sheep and cattle in a single oral dose. In the first trial, two groups of five sheep were used. They received 100 mg/kg body weight of either dl-α-tocopherol or its acetylated form. The blood plasma α-tocopherol tolerance curve area was higher in the dl-α-tocopherol group than in its ester form. The time to reach maximum plasma α-tocopherol concentration was less in the dl-α-tocopherol group than in its ester form. In a second trial, four heifers received the two forms (50 mg/kg body weight) in rotation after an appropriate washing period between the two dosings. Again, plasma tolerance curve area was greater in the cattle following administration of dl-α-tocopherol than its acetylated form.

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Bibliographic Details
Main Authors: Hidiroglou, Nick N., McDowell, Lee Russell, Balbuena, Osvaldo
Format: info:ar-repo/semantics/artículo biblioteca
Language:eng
Published: Elsevier 1989-07
Subjects:Ganado Bovino, Ovinos, Tocoferoles, Plasma Sanguíneo, Cattle, Sheep, Tocopherols, Blood Plasma,
Online Access:http://hdl.handle.net/20.500.12123/6861
https://www.sciencedirect.com/science/article/pii/S0022030289792961
https://doi.org/10.3168/jds.S0022-0302(89)79296-1
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