Canarypox virus expressing infectious bursal disease VP2 protein as immunogen for chickens

Canarypox viruses (CNPV) carrying the coding sequence of VP2 protein from infectious bursal disease virus (IBDV) were obtained. These viruses were able to express VP2 protein in vitro and to induce IBDV-neutralizing antibodies when inoculated in specific pathogen-free chickens demonstrating that CNPV platform is usefulness to develop immunogens for chickens.

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Bibliographic Details
Main Authors: Zanetti, Flavia Adriana, Conte Grand, María Daniela, Mitarotonda, Romina Cristina, Taboga, Oscar Alberto, Calamante, Gabriela
Format: info:ar-repo/semantics/artículo biblioteca
Language:eng
Published: Sociedade Brasileira de Microbiologia 2014-05
Subjects:Virus bursitis infecciosa, Pollo, Anticuerpos, Infectious bursal disease virus, Chickens, Antibodies, Canarypox Virus, Proteína VP2, VP2 Protein,
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059302/
http://hdl.handle.net/20.500.12123/3578
http://dx.doi.org/10.1590/S1517-83822014000100032
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