Osteosarcoma in the Skull of a Holstein Heifer

A-2-year-old heifer showed a mass on the frontal part of the skull. Cytological analysis displayed pleomorphic, polyedric and fusiform cells with extracellular hyaline material. Histologically, the excised mass showed proliferation of spindle-to-polyhedral cells that exhibited anisocytosis and anisocaryosis. Osteoid substance was demonstrated by Masson´s thricromic stain. Tumoral cells and osteoid expressed osteocalcin. This case report communicates a very rare osteosarcoma in the corneal process of a young heifer. As the heifer was previously dehorned, it is possible that this procedure was a predisposing factor for malignant growth.

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Bibliographic Details
Main Authors: Micheloud, Juan Francisco, Guidi, Maria Guadalupe, Gimeno, Eduardo Juan
Format: info:ar-repo/semantics/artículo biblioteca
Language:eng
Published: Brazilian Association of Veterinary Pathology 2014-12-22
Subjects:Heifers, Sarcoma, Animal Diseases, Cattle, Novilla, Enfermedades de los Animales, Ganado Bovino, Osteosarcoma,
Online Access:http://hdl.handle.net/20.500.12123/16862
https://bjvp.org.br/wp-content/uploads/2015/07/DOWNLOAD-FULL-ARTICLE-3-20881_2015_3_30_3_31.pdf
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