Improved ice-binding proteins based on twist constrained helices

The invention relates to a protein comprising at least one ice-binding alpha helix, wherein the ice-binding helix has a twist of less than 100 degrees per residue, preferably a twist of less than 99 degrees per residue, most preferably a twist of about 98.2 degrees per residue. The invention further relates to a composition comprising such protein. The invention further relates to the use of said protein or composition as a cryopreservation agent, as a gas hydrate inhibitor or in coatings for de-icing materials. Lastly, the invention furthermore relates to a method for cryopreserving an aqueous mixture using said protein and a method for producing said protein.

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Bibliographic Details
Main Authors: De Haas, Robbert Jan, de Vries, Rindert Jakob, Tas, Roderick, Voets, Ilja
Format: Patent biblioteca
Language:English
Subjects:Life Science,
Online Access:https://research.wur.nl/en/publications/improved-ice-binding-proteins-based-on-twist-constrained-helices
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