assessment of Cas9-driven genome editing in presence of DNA oligos in CML cells

assessment of Cas9-driven genome editing in presence of DNA oligos in CML cells

We assessed indels resulting from Cas9-induced genome editing in CML cells in the presence of guide-complementary DNA oligonucleotides intended to inhibit Cas9 activity. We amplified pre-determined loci that were target with the supplied guides or were expected to be off-target sites for these guides. The on-target loci are EMX1 and FANCF.

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Bibliographic Details
Main Authors: Swartjes, Thomas, Shang, Peng, Van Den Berg, Dennis T.M., Künne, Tim, Geijsen, Niels, Brouns, Stan J.J., van der Oost, John, Staals, Raymond H.J., Notebaart, Richard A.
Format: Dataset biblioteca
Published: Wageningen University & Research
Subjects:Homo sapiens,
Online Access:https://research.wur.nl/en/datasets/assessment-of-cas9-driven-genome-editing-in-presence-of-dna-oligo
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https://research.wur.nl/en/datasets/assessment-of-cas9-driven-genome-editing-in-presence-of-dna-oligo

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