Cas12a nickases

The present invention relates to the field of gene genome editing. In particular, it relates to the provision of a Cas12a enzyme having nickase activity, as well as the means and methods for the modification of a genomic locus of interest with a Cas12a enzyme having nickase activity and uses thereof.

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Bibliographic Details
Main Authors: van der Oost, John, Villegas Warren, Ricardo, Luteijn, Maartje Janneke, Staals, Raymond Hubert Josèphe, Wu, Wen Ying, De Vleesschauwer, David, D'Halluin, Katelijn, Meulewaeter, Frank
Format: Patent biblioteca
Language:English
Subjects:Life Science,
Online Access:https://research.wur.nl/en/publications/cas12a-nickases-3
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