A matter of fat : Epidemiological studies of dietary and plasma fatty acids in coronary heart disease
In countries like the Netherlands, patients surviving a myocardial infarction (MI) form a growing part of the population. This thesis evaluates how types of unsaturated fatty acids in the diet and their blood biomarkers are related to diabetes and long-term mortality risk after MI. Most studies were done in the Alpha Omega Cohort of 4837 post-MI patients. Higher intakes and blood levels of omega-3 fatty acids from fish were associated with a 30% lower risk of fatal coronary heart disease. A low blood level of linoleic acid predicted type 2 diabetes, although the utility of this biomarker in clinical practice is not yet clear. Odd-chain fatty acids in the blood, which reflect dairy intake, were affected by dietary fiber intake in post-MI patients. This may explain favourable associations with diabetes reported in the literature. This thesis provides important evidence for dietary guidelines for patients with coronary heart disease.
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Doctoral thesis biblioteca |
| Language: | English |
| Published: |
Wageningen University
|
| Subjects: | Life Science, |
| Online Access: | https://research.wur.nl/en/publications/a-matter-of-fat-epidemiological-studies-of-dietary-and-plasma-fat |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|