Complete genome sequence of thermophilic Bacillus smithii type strain DSM 4216T

Bacillus smithii is a facultatively anaerobic, thermophilic bacterium able to use a variety of sugars that can be derived from lignocellulosic feedstocks. Being genetically accessible, it is a potential new host for biotechnological production of green chemicals from renewable resources. We determined the complete genomic sequence of the B. smithii type strain DSM 4216T, which consists of a 3,368,778 bp chromosome (GenBank accession number CP012024.1) and a 12,514 bp plasmid (GenBank accession number CP012025.1), together encoding 3880 genes. Genome annotation via RAST was complemented by a protein domain analysis. Some unique features of B. smithii central metabolism in comparison to related organisms included the lack of a standard acetate production pathway with no apparent pyruvate formate lyase, phosphotransacetylase, and acetate kinase genes, while acetate was the second fermentation product.

Bibliographic Details

Main Authors:	Bosma, Elleke F., Koehorst, Jasper J., van Hijum, Sacha A.F.T., Renckens, Bernadet, Vriesendorp, Bastienne, van de Weijer, Tom, Schaap, Peter J., de Vos, Willem M., van der Oost, John, van Kranenburg, Richard
Format:	Article/Letter to editor biblioteca
Language:	English
Subjects:	Bacillus smithii, Biotechnology, Genome sequence, Lactic acid, Thermophile, Thermophilic bacillus,
Online Access:	https://research.wur.nl/en/publications/complete-genome-sequence-of-thermophilic-bacillus-smithii-type-st
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