Selection of oleaginous yeasts for fatty acid production

Background: Oleaginous yeast species are an alternative for the production of lipids or triacylglycerides (TAGs). These yeasts are usually non-pathogenic and able to store TAGs ranging from 20 % to 70 % of their cell mass depending on culture conditions. TAGs originating from oleaginous yeasts can be used as the so-called second generation biofuels, which are based on non-food competing "waste carbon sources". Results: In this study the selection of potentially new interesting oleaginous yeast strains is described. Important selection criteria were: a broad maximum temperature and pH range for growth (robustness of the strain), a broad spectrum of carbon sources that can be metabolized (preferably including C-5 sugars), a high total fatty acid content in combination with a low glycogen content and genetic accessibility. Conclusions: Based on these selection criteria, among 24 screened species, Schwanniomyces occidentalis (Debaromyces occidentalis) CBS2864 was selected as a promising strain for the production of high amounts of lipids.

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Bibliographic Details
Main Authors: Lamers, Dennis, van Biezen, Nick, Martens, Dirk, Peters, Linda, van de Zilver, Eric, Jacobs-van Dreumel, Nicole, Wijffels, René H., Lokman, Christien
Format: Article/Letter to editor biblioteca
Language:English
Subjects:Lipid production, Oleaginous yeast, Schwanniomyces occidentalis, TAG,
Online Access:https://research.wur.nl/en/publications/selection-of-oleaginous-yeasts-for-fatty-acid-production
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