A nodule-specific protein secretory pathway required for nitrogen-fixing symbiosis

The nitrogen-fixing symbiosis between Sinorhizobium meliloti and its leguminous host plant Medicago truncatula occurs in a specialized root organ called the nodule. Bacteria that are released into plant cells are surrounded by a unique plant membrane compartment termed a symbiosome. We found that in the symbiosis-defective dnf1 mutant of M. truncatula, bacteroid and symbiosome development are blocked. We identified the DNF1 gene as encoding a subunit of a signal peptidase complex that is highly expressed in nodules. By analyzing data from whole-genome expression analysis, we propose that correct symbiosome development in M. truncatula requires the orderly secretion of protein constituents through coordinated up-regulation of a nodule-specific pathway exemplified by DNF1

Bibliographic Details

Main Authors:	Wang, D., Griffitts, J., Starker, C., Fedorova, E., Limpens, E.H.M., Ivanov, S.E., Bisseling, T., Long, S.
Format:	Article/Letter to editor biblioteca
Language:	English
Subjects:	define, endoplasmic-reticulum, fixation, gene-expression, medicago-truncatula, membrane, mutants, plant, root-nodules, signal peptidase activity,
Online Access:	https://research.wur.nl/en/publications/a-nodule-specific-protein-secretory-pathway-required-for-nitrogen
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