Salmonella gene rma (ramA) and multiple-drug-resistant Salmonella enterica serovar typhimurium

MarA and its homologue, RamA, have been implicated in multidrug resistance (MDR). RamA overexpression in Salmonella enterica serovar Typhimurium and Escherichia coli conferred MDR independently of marA. Inactivation of ramA did not affect the antibiotic susceptibilities of wild-type S. enterica serovar Typhimurium or 15 unrelated clinical MDR isolates. Thus, ramA overexpression is not a common MDR mechanism in Salmonella

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Bibliographic Details
Main Authors: van Straaten, T., Janssen, R., Mevius, D.J., van Dissel, J.T.
Format: Article/Letter to editor biblioteca
Language:English
Subjects:antibiotic-resistance, confers, escherichia-coli, mutants, virulence,
Online Access:https://research.wur.nl/en/publications/salmonella-gene-rma-rama-and-multiple-drug-resistant-salmonella-e
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