Optimal parametric sensitivity control for a fed-batch reactor

The paper presents a method to derive an optimal parametric sensitivity controller for optimal estimation of a set of parameters in an experiment. The method is demonstrated for a fed batch bio-reactor case study for optimal estimation of the saturation constant Ks and, albeit intuitively, the parameter combination "mu-max X/Y" where mu-max is the maximum growth rate [g/min], Y is the yield coefficient [g/g], and X is the (constant) biomass [g].

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Bibliographic Details
Main Authors: Stigter, J.D., Keesman, K.J.
Format: Article in monograph or in proceedings biblioteca
Language:English
Subjects:Life Science,
Online Access:https://research.wur.nl/en/publications/optimal-parametric-sensitivity-control-for-a-fed-batch-reactor-2
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