First Girgensohnine Analogs Prepared Through InCl3-catalyzed Strecker Reaction and their Bioprospection
An efficient preparation of the girgensohnine and its close analogs with α-aminonitrile structure, and their spectral characterization were reported for the first time. The piperidine α-aminonitriles were obtained through 5 mol% InCl3-catalyzed one-pot Strecker reaction and tested for antioxidant activity and AChE inhibitory properties. It was found that girgensohnine possesses a moderate AChE inhibitory property while its spiroanalog shows good antioxidant capacity
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| Main Authors: | , |
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| Format: | Artículo científico biblioteca |
| Language: | eng |
| Published: |
2013
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| Subjects: | Biología vegetal, Productos químicos, Aceites vegetales, AChE inhibitory activity, Alkaloids, α-Aminonitriles, Antioxidant capacity, Girgensohnine, Strecker reaction, Aceites esenciales, Bioquímica vegetal, Biotecnología, Catalizadores, |
| Online Access: | http://repositorio.colciencias.gov.co/handle/11146/34174 |
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