Diastereoselective Synthesis of Dihydroisoindolo[2,1‑a]quinolin-11- ones by Solvent-Free AMCell-SO3H‑Catalyzed Imino Diels−Alder/Intramolecular Amide Cyclization Cascade Reactions
Nineteen bioactive highly functionalized 6,6a-dihydroisoindolo[2,1-a]quinolin-11(5H)-one derivatives were easily prepared in good yield without solvent using catalytic amorphous milled cellulose sulfonic acid (AMCell-SO3H), substituted anilines, propenyl-phenols, and phthaldehydic acid. The cascade reaction gave high regioselectivity and diastereoselectivity.
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Main Authors: | , |
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Format: | Artículo científico biblioteca |
Language: | eng |
Published: |
2014-04-30
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Subjects: | Biología vegetal, Aceites vegetales, Productos químicos, Biología molecular, Biotecnología, Aceites esenciales, Tecnología química, Química agrícola, |
Online Access: | http://repositorio.colciencias.gov.co/handle/11146/34169 |
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