Diastereoselective Synthesis of Dihydroisoindolo[2,1‑a]quinolin-11- ones by Solvent-Free AMCell-SO3H‑Catalyzed Imino Diels−Alder/Intramolecular Amide Cyclization Cascade Reactions

Nineteen bioactive highly functionalized 6,6a-dihydroisoindolo[2,1-a]quinolin-11(5H)-one derivatives were easily prepared in good yield without solvent using catalytic amorphous milled cellulose sulfonic acid (AMCell-SO3H), substituted anilines, propenyl-phenols, and phthaldehydic acid. The cascade reaction gave high regioselectivity and diastereoselectivity.

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Bibliographic Details
Main Authors: Merchan Arenas, Diego Rolando, Kouznetsov, Vladimir V.
Format: Artículo científico biblioteca
Language:eng
Published: 2014-04-30
Subjects:Biología vegetal, Aceites vegetales, Productos químicos, Biología molecular, Biotecnología, Aceites esenciales, Tecnología química, Química agrícola,
Online Access:http://repositorio.colciencias.gov.co/handle/11146/34169
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