Self-Assembly of Okadaic Acid as a Pathway to the Cell

The polyether toxin okadaic acid (OA) inhibits several protein serine/threonine phosphatases that play central roles in the regulation of many essential cellular processes. The use of scanning tunneling microscopy (STM) shows that dimerization of such toxins is crucial to understand the mechanism of toxin transport across model membranes.

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Bibliographic Details
Main Authors: Hernández Daranas, Antonio, Cruz, Patricia G., Hernández Creus, Alberto, Norte, Manuel, Fernández, José J.
Other Authors: Ministerio de Educación y Ciencia (España)
Format: artículo biblioteca
Language:English
Published: American Chemical Society 2007-09-15
Subjects:Potassium, Gold, Ions, Membranes, Scanning tunneling microscopy,
Online Access:http://hdl.handle.net/10261/213381
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