Self-Assembly of Okadaic Acid as a Pathway to the Cell
The polyether toxin okadaic acid (OA) inhibits several protein serine/threonine phosphatases that play central roles in the regulation of many essential cellular processes. The use of scanning tunneling microscopy (STM) shows that dimerization of such toxins is crucial to understand the mechanism of toxin transport across model membranes.
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Main Authors: | , , , , |
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Other Authors: | |
Format: | artículo biblioteca |
Language: | English |
Published: |
American Chemical Society
2007-09-15
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Subjects: | Potassium, Gold, Ions, Membranes, Scanning tunneling microscopy, |
Online Access: | http://hdl.handle.net/10261/213381 |
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