Lignans and an abundant flavone glycoside with free-radical scavenging activity from the roots of the endemic species Stachys mialhesi de Noé
Two sterols, stigmasterol (1) and β-sitosterol (2), two lignans, (+)-sesamin (3), new for the genus Stachys and (±)-paulownia (4), new in the Lamiaceae family, reported for the second time from a natural source, and one acetylated flavone glycoside isoscutellarein-7-O-(2>-O-6>′-O-acetyl-β-D-allopyranosyl-β-Dglucopyranoside (5), were isolated from the roots of Stachys mialhesi de Noé. Surprisingly, 3g of compound 5 are gathered from 5g of roots extract. The structures of compounds 1-5 were established on the basis of physical and spectroscopic analysis, and by comparison with the literature data. The free-radical-scavenging property of compound 5 was evaluated by the use of the ESR method in order to visualize the inhibition of the 1,1-diphenyl- 2-1picrylhydrazyl (DPPH) free radical.
| Main Authors: | , , , , , , , |
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| Format: | artículo biblioteca |
| Published: |
ACG Publications
2011-07-03
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| Subjects: | Stachys mialhesi, Lamiaceae, Lignans, Free radical scavenging activity, ESR, |
| Online Access: | http://hdl.handle.net/10261/205386 |
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