Synthesis of α,γ-peptide hybrids by selective conversion of glutamic acid units

The site-selective modification of small peptides at a glutamate residue allows the ready preparation of α,γ-hybrids. In this way, a single peptide can be transformed into a variety of hybrid derivatives. The process takes place under very mild conditions, and good global yields are obtained.

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Bibliographic Details
Main Authors: Saavedra, Carlos J., Boto, Alicia, Hernández, Rosendo
Other Authors: Ministerio de Ciencia e Innovación (España)
Format: artículo biblioteca
Published: ACS Publications 2012-06-25
Subjects:Peptide hybrids, Synthesis, Glutamic acid units, Selective conversion,
Online Access:http://hdl.handle.net/10261/193424
http://dx.doi.org/10.13039/501100004837
http://dx.doi.org/10.13039/501100007757
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