Bioactive constituents from transformed root cultures of Nepeta teydea

A phytochemical study of an extract from transformed root cultures of Nepeta teydea, induced by Agrobacterium rhizogenes, led to the isolation of the following new compounds: the sesquiterpene (-)-cinalbicol, the diterpene teydeadione (6,11,14-trihydroxy-12-methoxy-abieta-5,8,11,13,15-penten-7-one), a degraded C23-triterpene (teydealdehyde) and three fatty acid esters of lanosta-7,24-dien-3β-ol. The propyl ester of rosmarinic acid was also isolated for the first time from a natural source. In addition, two dehydroabietane diterpenes, eight triterpenes and eighteen known phenolic compounds were obtained. The antifeedant, cytotoxic and phytotoxic activities of the isolated compounds have also been investigated.

Saved in:
Bibliographic Details
Main Authors: Fraga, Braulio M., González-Coloma, Azucena, Alegre-Gómez, Sergio, López-Rodríguez, Matías, Amador, Leonardo J., Díaz, Carmen E.
Other Authors: Ministerio de Economía y Competitividad (España)
Format: artículo biblioteca
Published: Elsevier 2017-01
Subjects:Lamiaceae, Teydeadione, Biological activities, Phenolic compounds, Teydealdehyde, Nepeta teydea, Triterpenes, Transformed root cultures, Sesquiterpenes, (-)-Cinalbicol, Diterpenes,
Online Access:http://hdl.handle.net/10261/185077
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100003339
http://dx.doi.org/10.13039/501100003329
Tags: Add Tag
No Tags, Be the first to tag this record!