Actividad antioxidante de los polifelones de Hypogymnia tavaresii D. Hawksw. & P. James

Lichen substances have more than one phenolic hydroxyl group attached to one or more benzene rings, thus qualifying them as polyphenols. The secondary metabolites isolated from the lichen H. tavaresii have been studied in a bid to find compounds protective against oxidative stress and free radical-induced damage. The compounds were identified based on their MS and 1H-NMR spectra as well as retention factors of TLC analysis. In addition to the previously described metabolites (atranorin, chloroatranorin, physodic and physodalic acids) of H. tavaresii, a further three were identified in its thalli: 2'-O-methylphysodone, isophysodic and ursolic acids. The newly identified compounds of H. tavaresii thalli may be useful in the chemotaxonomic classification of this species. Antioxidant effectiveness of the acetone extract's fractions was measured. The compounds of the active fractions were purified and exhibited 180-800 fold less radical scavenging activity than the reference substance α-(+)-tocopherol in a DPPH• model expressed by IC values.

Bibliographic Details

Main Authors:	Rodríguez Pérez, Elsa M., Toledo Marante, Francisco J., Caballero Hernández, Josefa, Bermejo, Jaime, Estévez, Francisco
Other Authors:	Agencia Canaria de Investigación, Innovación y Sociedad de la Información
Format:	artículo biblioteca
Published:	Sociedade Brasileira de Química 2016
Subjects:	Scavengers, Depsides, Depsidones, Lichen, Tavaresii, Hypogymnia,
Online Access:	http://hdl.handle.net/10261/184181 http://dx.doi.org/10.13039/501100007757
Tags:	Add Tag No Tags, Be the first to tag this record!