A practical, catalytic and selective deprotection of a Boc group in N,N′-diprotected amines using iron(III)-catalysis
A selective, catalytic and practical method for removing a Boc group from several N,N′-diprotected amino acids and amine derivatives using iron(III) salts as sustainable catalysts is described. The process is clean, not needing a purification step. A theoretical study rationalizing the results with several metals is presented.
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Royal Society of Chemistry (UK)
2015
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| Online Access: | http://hdl.handle.net/10261/181264 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/501100000780 |
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dig-ipna-es-10261-1812642019-11-14T09:22:22Z A practical, catalytic and selective deprotection of a Boc group in N,N′-diprotected amines using iron(III)-catalysis López-Soria, Juan M. Pérez, Sixto J. Hernández, J. Nicolás Ramírez, Miguel A. Martín, Víctor S. Padrón, Juan I. Ministerio de Economía y Competitividad (España) European Commission A selective, catalytic and practical method for removing a Boc group from several N,N′-diprotected amino acids and amine derivatives using iron(III) salts as sustainable catalysts is described. The process is clean, not needing a purification step. A theoretical study rationalizing the results with several metals is presented. This research was co-financed by the Spanish MINECO (CTQ2011-28417-C02-01), the European Regional Development Fund (FEDER), the Spanish Ministerio de Educaci´on (Programa Campus de Excelencia Internacional CEI10/00018), and the EU Research Potential (FP7-REGPOT-2012-CT2012-31637-IMBRAIN). S. J. P. thanks the Spanish MINECO for a F. P. U. fellowship. Peer Reviewed 2019-05-13T09:48:34Z 2019-05-13T09:48:34Z 2015 2019-05-13T09:48:34Z artículo http://purl.org/coar/resource_type/c_6501 RSC Advances 5(9): 6647-6651 (2015) http://hdl.handle.net/10261/181264 10.1039/c4ra12143k 2046-2069 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/501100000780 #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/EC/FP7/316137 Publisher's version http://dx.doi.org/10.1039/c4ra12143k Sí open Royal Society of Chemistry (UK) |
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A selective, catalytic and practical method for removing a Boc group from several N,N′-diprotected amino acids and amine derivatives using iron(III) salts as sustainable catalysts is described. The process is clean, not needing a purification step. A theoretical study rationalizing the results with several metals is presented. |
| author2 |
Ministerio de Economía y Competitividad (España) |
| author_facet |
Ministerio de Economía y Competitividad (España) López-Soria, Juan M. Pérez, Sixto J. Hernández, J. Nicolás Ramírez, Miguel A. Martín, Víctor S. Padrón, Juan I. |
| format |
artículo |
| author |
López-Soria, Juan M. Pérez, Sixto J. Hernández, J. Nicolás Ramírez, Miguel A. Martín, Víctor S. Padrón, Juan I. |
| spellingShingle |
López-Soria, Juan M. Pérez, Sixto J. Hernández, J. Nicolás Ramírez, Miguel A. Martín, Víctor S. Padrón, Juan I. A practical, catalytic and selective deprotection of a Boc group in N,N′-diprotected amines using iron(III)-catalysis |
| author_sort |
López-Soria, Juan M. |
| title |
A practical, catalytic and selective deprotection of a Boc group in N,N′-diprotected amines using iron(III)-catalysis |
| title_short |
A practical, catalytic and selective deprotection of a Boc group in N,N′-diprotected amines using iron(III)-catalysis |
| title_full |
A practical, catalytic and selective deprotection of a Boc group in N,N′-diprotected amines using iron(III)-catalysis |
| title_fullStr |
A practical, catalytic and selective deprotection of a Boc group in N,N′-diprotected amines using iron(III)-catalysis |
| title_full_unstemmed |
A practical, catalytic and selective deprotection of a Boc group in N,N′-diprotected amines using iron(III)-catalysis |
| title_sort |
practical, catalytic and selective deprotection of a boc group in n,n′-diprotected amines using iron(iii)-catalysis |
| publisher |
Royal Society of Chemistry (UK) |
| publishDate |
2015 |
| url |
http://hdl.handle.net/10261/181264 http://dx.doi.org/10.13039/501100003329 http://dx.doi.org/10.13039/501100000780 |
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| _version_ |
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