A practical, catalytic and selective deprotection of a Boc group in N,N′-diprotected amines using iron(III)-catalysis

A selective, catalytic and practical method for removing a Boc group from several N,N′-diprotected amino acids and amine derivatives using iron(III) salts as sustainable catalysts is described. The process is clean, not needing a purification step. A theoretical study rationalizing the results with several metals is presented.

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Bibliographic Details
Main Authors: López-Soria, Juan M., Pérez, Sixto J., Hernández, J. Nicolás, Ramírez, Miguel A., Martín, Víctor S., Padrón, Juan I.
Other Authors: Ministerio de Economía y Competitividad (España)
Format: artículo biblioteca
Published: Royal Society of Chemistry (UK) 2015
Online Access:http://hdl.handle.net/10261/181264
http://dx.doi.org/10.13039/501100003329
http://dx.doi.org/10.13039/501100000780
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