Two novel abietane dimers from transformed root cultures of Salvia broussonetii
Broussonetone A (1) and broussonetone B (2), two novel dimeric abietane diterpenes, have been isolated from Salvia broussonetii root cultures transformed by Agrobacterium rhizogenes. The structure of broussonetone A was determined from spectroscopic data and confirmed by X-ray analysis. This dimer can be formed by a [4+2]-cycloaddition of two molecules of 13β-hydroxyabieta-8(14),9(11)-dien-12-one. NMR data of broussonetone B indicated that the C-20 methyl in part B of the broussonetone A molecule had been substituted by an aldehyde group. Thus, broussonetone B could be formed by an analogous Diels Alder reaction between 13β-hydroxyabieta-8(14),9(11)-dien-12-one as the dienophile and its 20-oxo derivative as the electrophile.
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| Main Authors: | , , |
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| Other Authors: | |
| Format: | artículo biblioteca |
| Published: |
Elsevier
2014-01-22
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| Subjects: | Transformed Root Cultures, Abietane, Broussonetone A, Broussonetone B, Diterpene Dimers, Salvia Broussonetii, |
| Online Access: | http://hdl.handle.net/10261/180414 http://dx.doi.org/10.13039/501100003329 |
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