Microbial transformation of the diterpene 7-epi-foliol by Fusarium fujikuroi
The incubation of 3,7,18-trihydroxy-ent-kaur-16-ene (7-epi-foliol) with the fungus Fusarium fujikuroi gave 3,7,18-trihydroxy-ent-kaur-16-en-18-al as the sole product. The biotransformation of other 7- or 7-hydroxy derivatives had led to the oxidation of C-19, which is a main step in the biosynthesis of gibberellins and kaurenolides. Now, the presence of the 3-hydroxyl impedes that oxidation, which is directed to the adjacent C-18 hydroxymethyl forming the corresponding aldehyde.
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| Main Authors: | , , , |
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| Other Authors: | |
| Format: | artículo biblioteca |
| Published: |
Sage Publications
2014
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| Subjects: | Diterpenes, 7-epi-Foliol, 18-Oxo-7-epi-foliol, Ent-Kaur-16-enes, Fusarium fujikuroi, Biotransformations, |
| Online Access: | http://hdl.handle.net/10261/180336 http://dx.doi.org/10.13039/501100003329 |
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