Efficient synthesis of benzocyclotrimer analogues by Negishi cross-coupling and intramolecular nucleophilic substitution

We report a new and efficient synthetic strategy that allows access to flexible and functionalized benzocyclotrimers under mild conditions and in few steps. The Negishi cross-coupling reaction was used for the C-C bond formation, whereas intramolecular O-alkylations provided the oxepane rings.

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Bibliographic Details
Main Authors: Borges-González, Jorge, Martín, Tomás
Format: artículo biblioteca
Published: Royal Society of Chemistry (UK) 2017-12-04
Subjects:synthesis, Negishi cross-coupling, Benzocyclotrimer,
Online Access:http://hdl.handle.net/10261/179517
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