Cembranoids from Eunicea sp. enhance insulin-producing cells proliferation

Nine new cembranoids 1–9 containing an α–methylene–γ–butyrolactone together with the known diterpenes 10–15 have been isolated from a crude extract of Eunicea sp. and their structures were established by spectroscopic methods. The proliferative effect of six of these compounds on insulin-producing cells (beta–cells) was evaluated.

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Bibliographic Details
Main Authors: Porras, G., Díaz-Marrero, Ana R., Rosa, José M. de la, D'Croz, Luis, Pablo, Nagore de, Perdomo, Germán, Cózar-Castellano, Irene, Darias, José, Cueto, Mercedes
Other Authors: Ministerio de Economía, Industria y Competitividad (España)
Format: artículo biblioteca
Published: Elsevier 2018-03-07
Subjects:Octocorals, Eunicea, Cembranoids, Beta-pancreatic cells,
Online Access:http://hdl.handle.net/10261/179475
http://dx.doi.org/10.13039/501100010198
http://dx.doi.org/10.13039/501100003339
http://dx.doi.org/10.13039/501100004837
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