Microwave-assisted diversity-oriented domino synthesis of functionalized nicotinic acid derivatives
The microwave-assisted diversity-oriented domino synthesis of functionalized alkyl nicotinates from propargyl vinyl ethers is described. The domino manifold comprises a complex network of reactions involving at least five distinct chemical steps. The obtained alkyl nicotinates incorporate two diversity points at the ring and one ester functionality as convenient handles for further elaboration. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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| Main Authors: | , , |
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| Other Authors: | |
| Format: | artículo biblioteca |
| Published: |
John Wiley & Sons
2010-10-22
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| Subjects: | Domino reactions, Electrocyclic reactions, Microwave chemistry, Nitrogen heterocycles, Nicotinic acid, |
| Online Access: | http://hdl.handle.net/10261/132586 http://dx.doi.org/10.13039/501100004837 http://dx.doi.org/10.13039/501100004587 http://dx.doi.org/10.13039/501100000780 |
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