Effect of bta-miR-483-3p of extracellular vesicles from the oviductal fluid of pregnant cows on in vitro early embryo development

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression and signalling pathways related to proliferation and differentiation in early embryo development through post-transcriptional mechanisms. A previous study showed that bta-mir 483-3p was exclusively detected in extracellular vesicles from the oviductal fluid of pregnant cows compared to non-pregnant (Mazzarella et al., 2021). Therefore, we aimed to determine whether bta-miR-483-3p is uptaken by bovine in vitro-produced embryos through passive transfection (gymnosis) and to evaluate the effect of miRNA supplementation on early embryo development and quality.

Bibliographic Details

Main Authors:	Mazzarella, Rosane, Cajas, Yulia N., Cañón-Beltrán, Karina, Gascón Collado, D., Beltrán Breña, Paula, Sánchez, José María, Fernández-Fuertes, Beatriz, Gutiérrez-Adán, Alfonso, González, E., Rizos, Dimitrios
Other Authors:	Mazzarella, Rosane [0000-0001-6860-8897]
Format:	comunicación de congreso biblioteca
Language:	English
Published:	Elsevier 2023-05-03
Online Access:	http://hdl.handle.net/10261/351410
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