Molecularly-imprinted polymers as a versatile, highly selective tool in sample preparation
Sample preparation is still considered the bottleneck of the whole analytical process. In this regard, improvement in selectivity during extraction and/or subsequent clean-up of sample extracts is an area of intense research activity. One of the most versatile, promising options is to incorporate molecularly-imprinted polymers (MIPs) into sample preparation. MIPs are tailor-made, stable polymers with molecular recognition abilities, so that they are excellent materials for providing selectivity in sample preparation. This review describes the use of MIPs in sample preparation, including solid-phase extraction, and corresponding recent improvements, and their recent incorporation into other extraction techniques (e.g.;solid-phase microextraction, matrix-solid phase dispersion and stir-bar sorptive extraction). It discusses the advantages and the drawbacks of each methodology, and the future expected trends. © 2013 Elsevier Ltd.
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| Format: | review biblioteca |
| Language: | English |
| Published: |
Elsevier
2013
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| Subjects: | Extraction, Matrix solid-phase dispersion (MSPD), Molecularly-imprinted polymer (MIP), Molecular recognition, Sample clean-up, Sample preparation, Selectivity, Solid-phase extraction (SPE), Solid-phase microextraction (SPME, Stir-bar sorptive extraction (SBSE), |
| Online Access: | http://hdl.handle.net/20.500.12792/2699 http://hdl.handle.net/10261/293475 |
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