Prevalence of Hepatitis E virus (HEV) antibodies in Mexican pigs

The hepatitis E virus (HEV) is the causative agent of Hepatitis E, an enterically transmitted disease. HEV infections in pigs and humans have been reported worldwide, but data from Mexico are scarce. In the present study, the prevalence of anti-HEV IgG antibodies was investigated in a quite large number of swine from Mexico by means of an ELISA based on a recombinant open reading frame 2 protein of HEV genotype 3. Serum samples from 683 healthy pigs (1–48 months old), collected during 2010–2013 in 109 herds from 48 municipalities located in 9 states in the centre of the country were assayed. A 30.75 % (210/683) of the sera tested were positive, and they were distributed along all the states included in the study. The prevalence of anti-HEV antibodies varied widely between municipalities and herds, and it was higher in pigs 4–6 months of age. No relationships were detected between seroprevalences and farm characteristics. Forty individual faecal samples were analysed by RT-PCR and all resulted negative. These data indicate that HEV infection is widespread in Mexican pigs; thus, representing a potential zoonotic risk for humans. © 2016, Springer Science+Business Media New York.

Saved in:
Bibliographic Details
Main Authors: Merino-Ramos, T., Martín-Acebes, M. A., Casal, J., Saiz Calahorra, Juan Carlos, Loza-Rubio, E.
Format: artículo biblioteca
Language:English
Published: Springer 2016
Subjects:HEV, Mexico, Pigs, Seroprevalence, ELISA, RNA,
Online Access:http://hdl.handle.net/20.500.12792/2878
http://hdl.handle.net/10261/292043
Tags: Add Tag
No Tags, Be the first to tag this record!