Antimicrobial activity of reuterin in combination with nisin against food-borne pathogens

Antimicrobial activity of reuterin individually or in combination with nisin against different food-borne Gram-positive and Gram-negative pathogens in milk was investigated. Reuterin (8 AU/ml) exhibited bacteriostatic activity against Listeria monocytogenes, whereas its activity was slightly bactericidal against Staphylococcus aureus at 37°C. Higher bactericidal activity was detected against Escherichia coli O157H7, Salmonella choleraesuis subsp. choleraesuis, Yersinia enterocolitica, Aeromonas hydrophila subsp. hydrophila and Campylobacter jejuni. A significant synergistic effect on L. monocytogenes and a slight additive effect on S. aureus after 24 h at 37°C were observed when reuterin was combined with nisin (100 IU/ml). The combination of reuterin with nisin did not enhance the antimicrobial effect of reuterin against Gram-negative pathogens. © 2004 Elsevier B.V. All rights reserved.

Bibliographic Details

Main Authors:	Arques Orobón, Juan Luis, Fernández, J., Gaya Sicilia, María Pilar, Núñez Gutiérrez, Manuel, Rodríguez Mínguez, Eva, Medina, M.
Format:	artículo biblioteca
Language:	English
Published:	Elsevier 2004
Subjects:	Reuterin, Nisin, Pathogens, Combined treatments,
Online Access:	http://hdl.handle.net/20.500.12792/1774 http://hdl.handle.net/10261/289877
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