Cocoa flavonoid epicatechin protects pancreatic beta cell viability and function against oxidative stress
[Scope] Diabetes mellitus is associated with reductions in glutathione, supporting the critical role of oxidative stress in its pathogenesis. Antioxidant food components such as flavonoids have a protective role against oxidative stress-induced degenerative and age-related diseases. Flavonoids such as epicatechin (EC) constitute an important part of the human diet; they can be found in green tea, grapes, and cocoa and possess multiple biological activities. This study investigates the chemo-protective effect of EC against oxidative stress induced by tert-butylhydroperoxide (t-BOOH) on Ins-1E pancreatic beta cells.
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| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | artículo biblioteca |
| Language: | English |
| Published: |
Wiley-VCH
2014
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| Subjects: | Antioxidant defences, Cocoa flavanols, Dietary polyphenols, Oxidative biomarkers, Type 2 diabetes mellitus, |
| Online Access: | http://hdl.handle.net/10261/93188 http://dx.doi.org/10.13039/501100003329 |
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