Sesquiterpene Lactones from Artemisia absinthium. Biotransformation and Rearrangement of the Insect Antifeedant 3α-hydroxypelenolide
Three new compounds, the sesquiterpenes absilactone and hansonlactone and the acetophenone derivative ajenjol, have been isolated from a cultivated variety of Artemisia absinthium. In addition, the major lactone isolated, 3α-hydroxypelenolide, was biotransformed by the fungus Mucor plumbeus affording the corresponding 1β, 10α-epoxide. A cadinane derivative was formed by an acid rearrangement produced in the culture medium, but not by the enzymatic system of the fungus. Furthermore, 3α-hydroxypelenolide showed strong antifeedant effects against Leptinotarsa decemlineata and cytotoxic activity to Sf9 insect cells, while the biotransformed compounds showed antifeedant postingestive effects against Spodoptera littoralis
Saved in:
| Main Authors: | , , , |
|---|---|
| Other Authors: | |
| Format: | artículo biblioteca |
| Language: | English |
| Published: |
Multidisciplinary Digital Publishing Institute
2021-04-28
|
| Subjects: | Artemisia absinthium, Asteraceae, Absilactone, Hansonlactone, Ajenjol, Mucor plumbeus, Biotransformations, 3α-hydroxypelenolide, Biological activities, |
| Online Access: | http://hdl.handle.net/10261/240067 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100004837 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|